Erythrocyte membrane proteins reactive with human (warm-reacting) anti-red cell autoantibodies.
نویسندگان
چکیده
منابع مشابه
Erythrocyte Membrane Proteins Reactive With IgG (Warm-Reacting) Anti-Red Blood Cell Autoantibodies: 11. Antibodies Coprecipitating
In our initial immunochemical study of the red blood cell (RBCI membrane proteins targeted in 20 cases of warmantibody autoimmune hemolytic anemia (AHA), RBC eluates of 6 patients mediated immunoprecipitation (IP) of both band 3 and glycophorin A (GPA). This dual IP pattern had previously been observed with murine monoclonal antibodies (MoAbs) against the high frequency blood group antigen, Wrb...
متن کاملErythrocyte Membrane Proteins Reactive With IgG (Warm-Reacting)
In our initial immunochemical study of the red blood cell (RBCI membrane proteins targeted in 20 cases of warmantibody autoimmune hemolytic anemia (AHA), RBC eluates of 6 patients mediated immunoprecipitation (IP) of both band 3 and glycophorin A (GPA). This dual IP pattern had previously been observed with murine monoclonal antibodies (MoAbs) against the high frequency blood group antigen, Wrb...
متن کاملErythrocyte membrane proteins reactive with IgG (warm-reacting) anti-red blood cell autoantibodies: II. Antibodies coprecipitating band 3 and glycophorin A.
In our initial immunochemical study of the red blood cell (RBC) membrane proteins targeted in 20 cases of warm-antibody autoimmune hemolytic anemia (AHA), RBC eluates of 6 patients mediated immunoprecipitation (IP) of both band 3 and glycophorin A (GPA). This dual IP pattern had previously been observed with murine monoclonal antibodies (MoAbs) against the high frequency blood group antigen, Wr...
متن کاملHow do I approach patients with warm-reactive autoantibodies?
W arm-reactive autoantibodies are the most common cause of autoimmune hemolytic anemia, with the incidence of these antibodies increasing with patient age. They have been reported in children as young as a few months of age, and there are two case reports of neonates who seem to have developed warm-reactive autoantibodies in utero. They are a relatively common finding at Arkansas Children’s Hos...
متن کاملArrangement of human erythrocyte membrane proteins.
The orientation of human erythrocyte membrane protein was examined by enzymic iodination using lactoperoxidase with the glucose-oxidase system for generating peroxide, followed by proteolytic digestion. The outer surface of intact cells was labeled with 125I and the cytoplasmic surface of either resealed ghosts containing lactoperoxidase or of inside-out vesicles was labeled with 131I. Followin...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1993
ISSN: 0021-9738
DOI: 10.1172/jci116376